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Evodenoson
|
DB12295 |
[Evodenoson has been used in trials studying the treatment of Open-angle Glaucoma and Ocular Hypertension.] |
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Puerarin
|
DB12290 |
[Puerarin has been investigated for the treatment of Alcohol Abuse.] |
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Tacedinaline
|
DB12291 |
[Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.] |
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Etomidate
|
DB00292 |
[Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.] |
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Chlorambucil
|
DB00291 |
[A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)] |
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Etonogestrel
|
DB00294 |
[Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]] |
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Raltitrexed
|
DB00293 |
[Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.] |
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Bleomycin
|
DB00290 |
[A complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.] |
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Propiverine
|
DB12278 |
[Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) [A32576].
Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the night to urinate). OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents [L2327], [L2328]. Overactive bladder syndrome affects millions of elderly individuals in the United States and shows equal prevalence in men and women. The impact of OAB on quality of life is sometimes devastating, especially to elderly patients with other medical conditions [L2328].
Propiverine hydrochloride is a bladder detrusor muscle relaxant drug with dual antimuscarinic and calcium-modulating properties for the treatment of OAB [L2317].] |
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OBP-801
|
DB12279 |
[OBP-801 has been used in trials studying the treatment of Solid Tumor.] |
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Aducanumab
|
DB12274 |
[Aducanumab has been used in trials studying the treatment of Alzheimer's Disease.] |
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Seviteronel
|
DB12275 |
[Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.] |
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Apomine
|
DB12276 |
[Apomine has been used in trials studying the treatment of Osteoporosis and Unspecified Adult Solid Tumor, Protocol Specific.] |
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Polihexanide
|
DB12277 |
[Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others.] |
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Losmapimod
|
DB12270 |
[Losmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.] |
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ORE-1001
|
DB12271 |
[ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.] |
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Vidupiprant
|
DB12272 |
[Vidupiprant has been used in trials studying the treatment and basic science of Asthma.] |
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Ecopipam
|
DB12273 |
[Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.] |
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Penciclovir
|
DB00299 |
[Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.] |
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Ropivacaine
|
DB00296 |
[Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.] |