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Selenomethionine
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DB11142 |
[Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. *In vivo*, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important antioxidant. In comparison to selenite, which is the inorganic form of selenium, the organic form of selenomethionine is more readily absorbed in the human body. Selenomethionin is used in biochemical laboratories where its incorporation into proteins that need to be visualized enhances the performance of X-ray crystallography.] |
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Piribedil
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DB12478 |
[Piribedil has been investigated in Parkinson's Disease.] |
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Zabofloxacin
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DB12479 |
[Zabofloxacin has been used in trials studying the treatment of Community Acquired Pneumonia and Chronic Obstructive Pulmonary Disease.] |
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Manganese gluconate
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DB11141 |
[Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement.] |
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Butamben
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DB11148 |
[Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate.[A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben was considered of low usability as it is only suitable to be used as a topical anesthesia. This belief changed with the introduction of epidural suspensions of butamben.[L2445] All butamben-containing products were removed from the market under the belief that it is unsafe or ineffective.[L2433]] |
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Levodropropizine
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DB12472 |
[Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).] |
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Aluminum zirconium pentachlorohydrate
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DB11147 |
[Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.] |
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Taurolidine
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DB12473 |
[Taurolidine has been investigated for the prevention of Central Venous Catheter, Home Parenteral Nutrition, and Catheter-Related Infections.] |
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Lynestrenol
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DB12474 |
[Lynestrenol has been used in trials studying the basic science of Transsexualism and Gender Dysphoria.] |
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Biphenyl dimethyl dicarboxylate
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DB12475 |
[Nissel has been investigated for the treatment of Chronic Liver Disease.] |
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Oxyquinoline
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DB11145 |
[Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.] |
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Dexelvucitabine
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DB12470 |
[Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.] |
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MK-3118
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DB12471 |
[SCY-078 has been used in trials studying the treatment of Mycoses, Candidemia, Candidiasis, Invasive, and Vulvovaginal Candidiasis.] |
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Chromium Cr-51
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DB11140 |
[Chromium Cr-51 is an isotope of chromium that is observationally stable. When intravenously administered, it is used as a diagnostic radiopharmaceutical agent to determine the red blood cell volume or mass, study the red blood cell survival time and evaluate blood loss [L1005].] |
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Phenindione
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DB00498 |
[An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)] |
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Oxycodone
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DB00497 |
[Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]] |
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Flutamide
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DB00499 |
[An antiandrogen with about the same potency as cyproterone in rodent and canine species.] |
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Entacapone
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DB00494 |
[Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa and a decarboxylase inhibitor.] |
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Cefotaxime
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DB00493 |
[Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).] |
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Darifenacin
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DB00496 |
[Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.] |