A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface. [ http://www.ncbi.nlm.nih.gov/pubmed/30422572 http://www.ncbi.nlm.nih.gov/pubmed/38032388 http://purl.obolibrary.org/obo/CL_CVS http://www.ncbi.nlm.nih.gov/pubmed/28400610 ]
Synonyms: multiciliated epithelial cell
Term information
cellxgene_subset
While the term 'multi-ciliated epithelial cell' refers to cells with multiple motile cilia, there are exceptions where epithelial cells may have multiple non-motile cilia. Examples include olfactory sensory neurons, which have non-motile cilia for sensory detection, and choroid plexus epithelial cells, which possess multiple non-motile cilia with transient motility during development. Multiciliated cells are essential for human health, and their dysfunction can lead to various diseases known as ciliopathies, such as primary ciliary dyskinesia. This condition affects the respiratory system, brain ventricles, and reproductive system, leading to chronic respiratory infections, hydrocephalus, and infertility
Term relations
- columnar/cuboidal epithelial cell and has part some motile cilium and has characteristic some multiciliated
- columnar/cuboidal epithelial cell
- ciliated epithelial cell
- has characteristic some multiciliated
- has part some motile cilium