N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.

Synonyms: EC 3.2.2.22 Polynucleotide Adenosine Glycosidase Proteins, Ribosome Inactivating Glycosidase, Polynucleotide Adenosine N-Glycosylases, rRNA RNA Glycosylase RNA N-Glycosidase Ribosome Inactivating Proteins N-Glycosidase, RNA RNA N Glycosidase Glycosylase, RNA rRNA N-Glycosylases rRNA N Glycosylases Adenosine Glycosidase, Polynucleotide Inactivating Proteins, Ribosome RIP (Ribosome Inactivating Proteins)