A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation.

Synonyms: Eukaryotic Elongation Factor 2 Kinase Calcium-Calmodulin-Dependent Protein Kinase Type 3 EF-2 Kinase Calmodulin-Dependent Protein Kinase III Calmodulin Dependent Protein Kinase III Elongation Factor 2 Kinase EC 2.7.11.20 eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III EF 2 Kinase E-2 Kinase Kinase CPK3, Protein Protein Kinase CPK3 Eukaryotic Elongation Factor-2 Kinase Kinase, EF-2 Cam PK III CAM Kinase III Calcium Calmodulin Dependent Protein Kinase Type 3 eEF 2 Specific Ca and Calmodulin Dependent Protein Kinase III E 2 Kinase