A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

Synonyms: Motilin Related Peptide Precursor Precursor, Ghrelin Gastric MLTRP Ghrelin Precursor Precursor, Motilin-Related Peptide Ppghrelin Ghrelin Obestatin Preprohormone 0 Motilin-Related Peptide Precursor Appetite Regulating Hormone Ghrelin PpMTLRP Ghrelin-Obestatin Preprohormone Motilin Related Peptide Peptide Precursor, Motilin-Related Appetite-Regulating Hormone Motilin-Related Peptide Obestatin GHRL Protein