This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.

Synonyms: A9 Antigen Antigen, A9 Tumor Specific Protein 180 Complex alpha(6)beta(4) Epithelial Integrin TSP-180 alpha(6)beta(4) Integrin alpha6 beta4 Integrin Integrin alpha6beta4 0 Integrin, alpha6 beta4 beta4 Integrin, alpha6 Tumor Specific Protein-180 Complex Integrin alpha(6),beta(4) alpha6beta4, Integrin Laminin-5 Receptor (alpha6beta4 Integrin)