An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Synonyms: Uridine, 2'-deoxy-5-fluoro- Fluorodeoxyuridine 039LU44I5M 5-FUdR 5-Fluorodeoxyuridine FUdR 5 Fluorodeoxyuridine Floxuridine
Term information
use FLOXURIDINE to search FLUORODEOXYURIDINE 1966-92
93; was FLUORODEOXYURIDINE 1963-92; FLOXURIDINE was see FLUORODEOXYURIDINE 1976-92
an antiviral & antineoplastic antimetabolite