Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

Synonyms: R-14950 Sibelium C11102TO53 R 14950 R14950 R7PLA2DM0J Flunarizine Dihydrochloride Flunarizine Flunarizin 0 Dihydrochloride, Flunarizine Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)- Flunarizine Hydrochloride Hydrochloride, Flunarizine