4-Aminopyridine
|
D015761 |
[One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes.
] |
4-Butyrolactone
|
D015107 |
[One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
] |
4-Chloro-7-nitrobenzofurazan
|
D009327 |
[A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.
] |
4-Chloromercuribenzenesulfonate
|
D002731 |
[A cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
] |
4-Hydroxyaminoquinoline-1-oxide
|
D015108 |
[A potent mutagen and carcinogen. It is a reduction product of 4-NITROQUINOLINE-1-OXIDE. It binds with nucleic acids and inactivates both bacteria and bacteriophage.
] |
4-Hydroxybenzoate-3-Monooxygenase
|
D015109 |
[A flavoprotein that catalyzes the synthesis of protocatechuic acid from 4-hydroxybenzoate in the presence of molecular oxygen. EC 1.14.13.2.
] |
4-Hydroxycoumarins
|
D015110 |
[Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants.
] |
4-Hydroxyphenylpyruvate Dioxygenase
|
D015111 |
[An enzyme that catalyzes the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. EC 1.13.11.27.
] |
4-Nitrophenylphosphatase
|
D009597 |
[An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is probably ACID PHOSPHATASE (EC 3.1.3.2); at alkaline pH it is probably ALKALINE PHOSPHATASE (EC 3.1.3.1). EC 3.1.3.41.
] |
4-Nitroquinoline-1-oxide
|
D015112 |
[A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
] |
4-Quinolones
|
D042462 |
[QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
] |
46, XX Disorders of Sex Development
|
D058489 |
[Congenital conditions in individuals with a female karyotype, in which the development of the gonadal or anatomical sex is atypical.
] |
46, XX Testicular Disorders of Sex Development
|
D058531 |
[Congenital conditions in individuals in which male GONADS develop in a genetic female (female to male sex reversal).
] |
5' Flanking Region
|
D024506 |
[The region of DNA which borders the 5' end of a transcription unit and where a variety of regulatory sequences are located.
] |
5' Untranslated Regions
|
D020121 |
[The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
] |
5'-Nucleotidase
|
D015720 |
[A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.
] |
5,10-Methylenetetrahydrofolate Reductase (FADH2)
|
D045103 |
[An FAD-dependent oxidoreductase found primarily in BACTERIA. It is specific for the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This enzyme was formerly listed as EC 1.1.1.68 and 1.1.99.15.
] |
5,6-Dihydroxytryptamine
|
D015115 |
[Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.
] |
5,7-Dihydroxytryptamine
|
D015116 |
[Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.
] |
5,8,11,14-Eicosatetraynoic Acid
|
D015117 |
[A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).
] |