All individuals in MeSH

Label Id Description
Bone Morphogenetic Protein 15 D055430 [A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the gene for bone morphogenetic protein 15 are linked to reproductive abnormalities such as PREMATURE OVARIAN FAILURE. ]
Bone Morphogenetic Protein 2 D055396 [A potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into OSTEOBLASTS. ]
Bone Morphogenetic Protein 3 D055398 [A bone morphogenetic protein that is found at high concentrations in a purified osteoinductive protein fraction from BONE. Bone morphogenetic protein 3 is referred to as osteogenin, however it may play a role in variety of developmental processes. ]
Bone Morphogenetic Protein 4 D055415 [A bone morphogenetic protein that is a potent inducer of bone formation. It also functions as a regulator of MESODERM formation during EMBRYONIC DEVELOPMENT. ]
Bone Morphogenetic Protein 5 D055417 [A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears. ]
Bone Morphogenetic Protein 6 D055418 [A bone morphogenetic protein that is a potent inducer of BONE formation. It plays additional roles in regulating CELL DIFFERENTIATION of non-osteoblastic cell types and epithelial-mesenchymal interactions. ]
Bone Morphogenetic Protein 7 D055419 [A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ]
Bone Morphogenetic Protein Receptors D052004 [A family of CELL SURFACE RECEPTORS that bind BONE MORPHOGENETIC PROTEINS. They are PROTEIN-SERINE-THREONINE KINASES that mediate SIGNAL TRANSDUCTION PATHWAYS through SMAD PROTEINS. ]
Bone Morphogenetic Protein Receptors, Type I D052005 [A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS. They can interact with and undergo PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II. They signal primarily through RECEPTOR-REGULATED SMAD PROTEINS. ]
Bone Morphogenetic Protein Receptors, Type II D052006 [A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS. They are constitutively active PROTEIN-SERINE-THREONINE KINASES that can interact with and phosphorylate TYPE I BONE MORPHOGENETIC PROTEIN RECEPTORS. ]
Bone Morphogenetic Proteins D019485 [Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. ]
Bone Nails D001858 [Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones. ]
Bone Neoplasms D001859 [Tumors or cancer located in bone tissue or specific BONES. ]
Bone Plates D001860 [Implantable fracture fixation devices attached to bone fragments with screws to bridge the fracture gap and shield the fracture site from stress as bone heals. (UMDNS, 1999) ]
Bone Regeneration D001861 [Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone. , A physiological phenomenon of BONE TRANSPLANTATION, whereby the new graft matrix configures a scaffold on which cells in the recipient form new bone. ]
Bone Remodeling D016723 [The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. ]
Bone Resorption D001862 [Bone loss due to osteoclastic activity. ]
Bone Retroversion D060751 [Attachment of a bone in which its head and neck is rotated excessively backward. ]
Bone Screws D001863 [Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures. ]
Bone Substitutes D018786 [Synthetic or natural materials for the replacement of bones or bone tissue. They include hard tissue replacement polymers, natural coral, hydroxyapatite, beta-tricalcium phosphate, and various other biomaterials. The bone substitutes as inert materials can be incorporated into surrounding tissue or gradually replaced by original tissue. ]