|
Astringents
|
D001252 |
[Agents, usually topical, that cause the contraction of tissues for the control of bleeding or secretions.
] |
|
Astrocytes
|
D001253 |
[A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
] |
|
Astrocytoma
|
D001254 |
[Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
] |
|
Astrology
|
D001255 |
[System of thought regarding forecasting of earthly and human events through the observation and interpretation of the fixed stars and planetary bodies.
] |
|
Astronauts
|
D018480 |
[Members of spacecraft crew including those who travel in space, and those in training for space flight.
] |
|
Astronomical Objects
|
D055587 |
[Aggregates of matter in outer space.
] |
|
Astronomical Phenomena
|
D055580 |
[Aggregates of matter in outer space, such as stars, planets, and comets; their properties; and the processes they undergo.
] |
|
Astronomy
|
D001256 |
[The science concerned with celestial bodies and the observation and interpretation of the radiation received in the vicinity of the earth from the component parts of the universe (McGraw Hill Dictionary of Scientific and Technical Terms, 5th ed)
] |
|
Astroviridae
|
D019200 |
[A family of RNA viruses with two genera: MAMASTROVIRUS and AVASTROVIRUS. They cause GASTROENTERITIS in humans and also infect other vertebrates.
] |
|
Astroviridae Infections
|
D019350 |
[Infections with ASTROVIRIDAE, causing gastroenteritis in human infants, calves, lambs, and piglets.
] |
|
Asymmetric Cell Division
|
D060049 |
[Unequal cell division that results in daughter cells of different sizes.
, Type of cell division of stem cells resulting in one daughter cell identical to the original stem cell and another non-stem daughter cell. This type of cell differentiation is achieved by asymmetrical segregation of cell fate determinants (see CELL POLARITY) and orientation of the MITOTIC SPINDLE in the context of intrinsic and extrinsic cues (STEM CELL NICHE).
] |
|
Asymptomatic Diseases
|
D058070 |
[Diseases that do not exhibit symptoms.
] |
|
Asymptomatic Infections
|
D058345 |
[Infections that do not exhibit symptoms.
] |
|
Atadenovirus
|
D046808 |
[A genus of ADENOVIRIDAE that comprises viruses of several species of MAMMALS and BIRDS. The type species is Ovine adenovirus D.
, A species of adenovirus comprising Bovine adenovirus serotypes 4-8.
, A strain of DUCK ADENOVIRUS A.
] |
|
Ataxia
|
D001259 |
[Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
] |
|
Ataxia Telangiectasia
|
D001260 |
[An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
] |
|
Ataxia Telangiectasia Mutated Proteins
|
D064007 |
[A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
] |
|
Ataxin-1
|
D000067696 |
[A chromatin-binding factor that represses Notch signaling and associates with RNA. Expansion of the polyglutamine tract by expanded CAG repeats in the ATXN1 gene coding region is associated with SPINOCEREBELLAR ATAXIA 1.
] |
|
Ataxin-10
|
D000067736 |
[An ataxin that is associated with the survival of cerebellar neurons. Expansion of the ATTCT pentanucleotide in the ATXN10 coding region is associated with SPINOCEREBELLAR ATAXIA 10.
] |
|
Ataxin-2
|
D000067698 |
[A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.
] |
