An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION.

Synonyms: BTAK Protein, Aurora Kinases A, Serine Threonine Protein Kinase 15, EC 2.7.11.1, Aurora A Kinases, AuroraA Kinase, Breast-Tumor-Amplified Kinase, Serine-Threonine Protein Kinase 15, STK15 Kinase, AURORA2 Protein, AURKA, Aurora Kinase A, Breast Tumor Amplified Kinase, Aurora A Kinase, Aurora-A Kinase

Instance information

comment

2014 ,2014; was indexed under PROTEIN SERINE-THREONINE KINASES 1995-2013

identifier

D064096

Instance relations