A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.
Synonyms: 0, Axin Signaling Complex Proteins, Axin Signaling Complex, Destruction Complex, beta-Catenin, Signaling Complex, Axin, beta-Catenin Destruction Complex, beta Catenin Destruction Complex
Instance information
comment
2012
identifier
D060465