A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Synonyms: EC 3.5.1.23, Acid Ceramidase
Instance information
comment
2009; see CERAMIDE TRIHEXOSIDASE 1983-2008 ,2009(1982); use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008
identifier
D055573
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Types