Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.

Synonyms: beta-Secretase, Secretases, alpha Secretase, EC 3.4.-, APP Secretase, gamma-Secretase, alpha-Secretase, Amyloid Precursor Protein Secretase, Amyloid Precursor Protein Secretases, beta Secretase, gamma Secretase, Secretase, APP, Secretase