A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
Synonyms: 136894-56-9, Basigin, Antigen, CD147, CD147 Antigen, CD147 Antigens, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Emmprin Protein, Basigin Protein, Antigens, CD147, Emmprin
Instance information
2018; see ANTIGENS, CD147 2006-2017; BASIGIN was indexed under ANTIGENS, CD 2005; under ANTIGENS, SURFACE and BLOOD PROTEINS 1990-2004; under MEMBRANE GLYCOPROTEINS 1993-2004; and under GLYCOPROTEINS 1990-1992 ,2018 (1990)
D051926