A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
Synonyms: c-IAP1 Protein, IAP2 Protein, Baculoviral Inhibitor Of Apoptosis Repeat Proteins, Inhibitor of Apoptosis Proteins, BIRC2 Protein, IAP Repeat Containing Proteins, IAP Protein (Apoptosis), Apoptosis Proteins Inhibitor, Baculoviral IAP Repeat-Containing 2 Protein, Inhibitor-Of-Apoptosis Protein, EC 2.3.2.27, 0, Baculoviral IAP Repeat Containing Protein 2, Baculoviral IAP Repeat Containing 2 Protein, Cellular Inhibitor of Apoptosis 1 Protein, cIAP1 Protein, Inhibitor of Apoptosis 2 Protein, Inhibitor Of Apoptosis Protein
Instance information
2006; INHIBITOR OF APOPTOSIS PROTEINS was indexed under PROTEINS 1997-2005 ,APOPTOSIS REGULATORY PROTEINS is also available ,2006(1997)
D051034