A ZINC metalloenzyme that catalyzes the transfer of a methyl group from BETAINE to HOMOCYSTEINE to produce dimethylglycine and METHIONINE, respectively. This enzyme is a member of a family of ZINC-dependent METHYLTRANSFERASES that use THIOLS or selenols as methyl acceptors.

Synonyms: S-Methyltransferase, Betaine-Homocysteine, Bet-HCys MTase, MTase, Bet-HCys, Betaine Homocysteine Methyltransferase 2, Betaine-Homocysteine Methyltransferase 2, EC 2.1.1.5, Methyltransferase 2, Betaine-Homocysteine, Betaine-Homocysteine Methyltransferase, Methyltransferase, Betaine Homocysteine, Betaine Homocysteine S Methyltransferase, Betaine Homocysteine Methyltransferase, Betaine-Homocysteine S-Methyltransferase, Methyltransferase-2, Betaine-Homocysteine, Bet HCys MTase, Betaine-Homocysteine Methyltransferase-2, Homocysteine Methyltransferase, Betaine, Methyltransferase, Betaine-Homocysteine