An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Synonyms: 0, Interferon Regulatory Factor-3, Interferon Regulatory Factor 3, IRF-3 Transcription Factor, IFN-Regulatory Factor 3, IRF 3 Transcription Factor, IFN Regulatory Factor 3, Transcription Factor, IRF-3
Instance information
comment
2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005 ,2006(1996)
identifier
D050838