A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.

Synonyms: 0, ISGF3, Transcription Factor, Interferon Stimulated Gene Factor 3, Transcription Factor, ISGF3, Interferon-Stimulated Gene Factor 3, ISGF3 Factor, ISGF3 Transcription Factor, IFN-Stimulated Gene Factor 3 Complex, Transcription Factor ISGF3, IFN Stimulated Gene Factor 3 Complex