The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
Synonyms: Squalene Monooxygenase, Squalene Monooxygenase (2,3-Epoxidizing), EC 1.14.14.17, Squalene Epoxidase, Epoxidase, Squalene, Monooxygenase, Squalene
Instance information
comment
2006; SQUALENE MONOOXYGENASE was indexed under OXYGENASES 1981-2005 & ETHERS, CYCLIC 1970-1980 ,2006(1980); use ETHERS, CYCLIC 1970-1979
identifier
D050603
Instance relations
Types