A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.

Synonyms: 14 3 3 zeta Protein, 14 3 3 beta Protein, 14-3-3 Protein, eta Isoform, 14 3 3 tau Protein, Protein, 14-3-3tau, Brain 14-3-3 Protein, 14 3 3eta Protein, 14 3 3epsilon Protein, 14-3-3 Protein, tau Isoform, 14-3-3 gamma Protein, 14-3-3epsilon Protein, 14 3 3 Proteins, 14-3-3 Protein, gamma Isoform, 14-3-3 eta Protein, 14-3-3 Protein, Brain, 14 3 3 Protein, zeta Isoform, 14-3-3 Protein, zeta Isoform, 14 3 3 Protein, 14 3 3zeta Protein, 14-3-3tau Protein, 14-3-3beta Protein, 14 3 3 Protein, epsilon Isoform, 14 3 3 Protein, eta Isoform, eta Protein, 14-3-3, 14-3-3gamma Protein, 14-3-3zeta Protein, Brain 14 3 3 Protein, 14-3-3 Protein, 14 3 3beta Protein, 14-3-3 beta Protein, 14 3 3 epsilon Protein, 0, 14 3 3 gamma Protein, 14-3-3 Protein, epsilon Isoform, 14 3 3gamma Protein, 14-3-3eta Protein, 14-3-3 Protein, beta Isoform, 14 3 3 eta Protein, 14 3 3 Protein, tau Isoform, 14 3 3tau Protein, 14 3 3 Protein, beta Isoform, 14 3 3 Protein, gamma Isoform, 14-3-3 Proteins, 14-3-3 epsilon Protein, 14-3-3 zeta Protein, 14-3-3 tau Protein, Protein 14-3-3