A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.

Synonyms: 0, TNF Receptor Ligands, Tumor Necrosis Factors, Necrosis Factors, Tumor, Receptor Ligands, TNF, Tumor Necrosis Factor Superfamily Ligands

Instance information

comment

2005

identifier

D048069