An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
Synonyms: Anhydrase, Organophosphorus Acid, Organophosphorus Acid Hydrolase, Paraoxonase 2, Paraoxonase 1, Organophosphorus Hydrolase, Anhydrolase, Organophosphorus Acid, Organophosphorus Acid Anhydrase, Aryldialkylphosphatase, Phosphatase, Aryl-dialkyl, Homocysteine Thiolactone Hydrolase, Hydrolase, Homocysteine Thiolactone, Enzyme, OPH, Hydrolase, Organophosphorus Acid, Acid Anhydrase, Organophosphorus, OPA Anhydrase, Aryl-dialkyl Phosphatase, Paraoxonase-2, Paraoxonase, Hydrolase, Organophosphorus, Arylalkylphosphatase, Acid Anhydrolase, Organophosphorus, Paraoxonase-1, OPH Enzyme, Thiolactone Hydrolase, Homocysteine, Acid Hydrolase, Organophosphorus, Organophosphorus Acid Anhydrolase, Anhydrase, OPA, Aryl dialkyl Phosphatase, EC 3.1.8.1
Instance information
entry terms PARAOXONASE-1, and PARAOXONASE-2 see SCR for organism specific terms ,2004; use ARYLDIALKYLPHOSPHATASE (NM) 1980 - 2003 ,2004; ARYLDIALKYLPHOSPHATASE was indexed under ESTERASES 1994-2003; PHOSPHORIC MONOESTER HYRDOLASES 1990-1993; PHOSPHOMONOESTERASES 1982-1989
D043303