QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.

Synonyms: 4 Quinolinone, 4 Oxoquinolines, 4 Quinolinones, 4-Quinolone, 4-Quinolones, 4-Oxoquinoline, 0, 4 Quinolone, 4-Quinolinone, 4-Oxoquinolines, 4 Quinolones, 4-Quinolinones, 4 Oxoquinoline