DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.

Synonyms: Hook, AT, AT Hook, AT Hook Motifs, Motif, AT Hook, Hooks, AT, AT-Hook Motif, Motifs, AT Hook, Motifs, AT-Hook, Motif, AT-Hook, AT-Hook Motifs, AT Hook Motif, AT Hooks