Alternatives to the use of animals in research, testing, and education. The alternatives may include reduction in the number of animals used, replacement of animals with a non-animal model or with animals of a species lower phylogenetically, or refinement of methods to minimize pain and distress of animals used.

Synonyms: Use Alternative, Animal, Use Alternatives, Animal, Alternative, Animal Use, Animal Use Alternatives, Animal Use Alternative, Alternatives, Animal Use, Animal Testing Reduction, Refinement and Replacement