An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.

Synonyms: DH2M523P0H, Genistein, Genestein

Instance information

comment

98; GENISTEIN was indexed under ISOFLAVONES 1976-97 ,98; use GENISTEIN (NM) 1980-97

identifier

D019833

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