An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
Synonyms: DH2M523P0H, Genistein, Genestein
Instance information
comment
98; GENISTEIN was indexed under ISOFLAVONES 1976-97 ,98; use GENISTEIN (NM) 1980-97
identifier
D019833