An enzyme that catalyzes the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. (Enzyme Nomenclature, 1992)

Synonyms: Chondroitinase ABC, Chondroitin ABC Lyase, Chondroitin Sulfate ABC Endolyase, chondroitin ABC lyase, EC 4.2.2.20, Chondroitin-Sulfate-ABC Endolyase