Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.

Synonyms: Animal growth regulators, transforming growth factors, Growth Factor, Transforming, 76057-06-2, Transforming Growth Factor, Growth Factors, Transforming, Factor, Transforming Growth, Transforming Growth Factors, Factors, Transforming Growth