A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.

Synonyms: Imd2, Immunodeficiency 2, Immunodeficiency 2s, Wiskott Aldrich Syndrome, Eczema Thrombocytopenia Immunodeficiency Syndrome, Aldrich Syndrome, Wiskott-Aldrich Syndrome, Wiskott Syndromes, Eczema-Thrombocytopenia-Immunodeficiency Syndromes, Wiskott Syndrome, Eczema-Thrombocytopenia-Immunodeficiency Syndrome