Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).

Synonyms: RNA Polymerase, DNA-Directed, EC 2.7.7.6, DNA Directed RNA Polymerases, Transcriptase, DNA-Directed RNA Polymerase, Polymerase, RNA, DNA Dependent RNA Polymerases, Polymerases, RNA, RNA Polymerases, DNA-Directed, 0, DNA-Dependent RNA Polymerases, DNA-Directed RNA Polymerases, Polymerase, DNA-Directed RNA, Nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed), RNA Polymerases, DNA Directed RNA Polymerase, Polymerases, DNA-Dependent RNA, Polymerases, DNA-Directed RNA, RNA Polymerases, DNA-Dependent, RNA Polymerase, Transcriptases