Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

Synonyms: Factor V, Blood-coagulation factor V, AC Globulin, 9001-24-5, Factor 5, Proaccelerin, Factor V, Coagulation, Blood Coagulation Factor V, Factor Pi, Coagulation Factor V, Factor Five