Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.

Synonyms: Chondroitin Sulfate Lyase, EC 4.2.2.-, Chondroitin Lyases, Lyases, Chondroitin, 0, Eliminase, Chondroitin, Chondroitin B Lyase, Lyase, Chondroitin AC, Lyase, Chondroitin Sulfate, Chondroitinase AC II, Chondroitin AC Lyase, Chondroitin Eliminase, Chondroitinase-AC II, Lyase, Chondroitin B, Sulfate Lyase, Chondroitin