Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Synonyms: Inhibitors, Cholinesterase, Anti-Cholinesterases, Irreversible Cholinesterase Inhibitors, Drugs, Anticholinesterase, Reversible Cholinesterase Inhibitors, Inhibitor, Cholinesterase, Cholinesterase Inhibitors, Reversible, Anticholinesterase Agents, Anticholinesterase Drug, Anti-Cholinesterase, Acetylcholinesterase Inhibitor, Drug, Anticholinesterase, Acetylcholinesterase Inhibitors, Agent, Anticholinesterase, Anticholinesterases, Inhibitor, Acetylcholinesterase, Inhibitors, Reversible Cholinesterase, Cholinesterase Inhibitors, Cholinesterase Inhibitors, Irreversible, Anticholinesterase, Cholinesterase Inhibitor, Inhibitors, Irreversible Cholinesterase, Anti Cholinesterase, 0, Agents, Anticholinesterase, Anti Cholinesterases, Inhibitors, Acetylcholinesterase, Anticholinesterase Agent, Anticholinesterase Drugs