Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Synonyms: Edema, Cytotoxic Brain, Edema, Brain, Cerebral Edemas, Vasogenic, Brain Swellings, Edema, Cerebral, Brain Edema, Vasogenic Brain Edema, Edema, Vasogenic Brain, Cerebral Edema, Vasogenic, Brain Edema, Vasogenic, Cytotoxic Brain Edema, Brain Swelling, Edema, Intracranial, Cerebral Edema, Cytotoxic, Edema, Cytotoxic Cerebral, Intracranial Edema, Vasogenic Cerebral Edema, Cytotoxic Cerebral Edema, Edema, Vasogenic Cerebral, Cerebral Edema, Brain Edema, Cytotoxic, Swelling, Brain