A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Synonyms: Presenile Alzheimer Dementia, Familial Alzheimer Disease (FAD), Alzheimer Diseases, Alzheimers Diseases, Alzheimer Disease, Early Onset, Dementia, Primary Senile Degenerative, Alzheimer Syndrome, Acute Confusional Senile Dementia, Alzheimer Type Senile Dementia, Dementia, Alzheimer Type, Focal Onset Alzheimer's Disease, Early Onset Alzheimer Disease, Late Onset Alzheimer Disease, Alzheimer Dementia, Alzheimer Disease, Familial (FAD), Alzheimer Sclerosis, Primary Senile Degenerative Dementia, Presenile Dementia, Dementia, Presenile, Alzheimer Dementias, Dementia, Alzheimer, Dementia, Senile, Senile Dementia, Dementia, Alzheimer-Type (ATD), Alzheimer Disease, Alzheimer's Disease, Focal Onset, Alzheimer Type Dementia, Alzheimer's Diseases, Alzheimer Disease, Late Onset, Sclerosis, Alzheimer, Alzheimer-Type Dementia (ATD), Alzheimer's Disease, Senile Dementia, Alzheimer Type, Senile Dementia, Acute Confusional, Familial Alzheimer Diseases (FAD), Alzheimer Type Dementia (ATD)