A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.

Synonyms: Methanone, (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)-, SOM0226, 0, CIF6334OLY, Tolcapone, 3,4-Dihydroxy-5'-methyl-5-nitrobenzophenone, Ro 40 7592, Ro 407592, 3,4 Dihydroxy 5' methyl 5 nitrobenzophenone, Tasmar, Ro 40-7592, Ro407592, Ro-40-7592