A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.

Synonyms: BIRC3 Protein, IAP1 Protein, Hiap-1 Protein, cIAP2 Protein, Baculoviral IAP Repeat-Containing 3 Protein, Cellular Inhibitor of Apoptosis 2, c-IAP2 Protein, Apoptosis-2 Cellular Inhibitor, EC 2.3.2.27, Inhibitor of Apoptosis 1 Protein, Cellular Inhibitor of Apoptosis-2, Hiap 1 Protein, Apoptosis Inhibitor 2, Baculoviral IAP Repeat Containing Protein 3, Inhibitor of Apoptosis Protein 1, Baculoviral IAP Repeat Containing 3 Protein, Inhibitor 2, Apoptosis