A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.

Synonyms: Peroxisome Assembly Factor-1, Peroxisomal Biogenesis Factor 2, Peroxisome Assembly Factor 1, Peroxin-2, 135847-86-8, Peroxisome Biogenesis Factor 2, Peroxin 2, Peroxisomal Membrane Protein 35, PMP35

Instance information

comment

2018 (1991) ,2018; see PEROXISOME ASSEMBLY FACTOR-1 1991-2017; PEROXISOMAL BIOGENESIS FACTOR 2 was indexed under MEMBRANE PROTEINS 1991-2017

identifier

D000074428