A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.
Synonyms: Peroxisome Assembly Factor-1, Peroxisomal Biogenesis Factor 2, Peroxisome Assembly Factor 1, Peroxin-2, 135847-86-8, Peroxisome Biogenesis Factor 2, Peroxin 2, Peroxisomal Membrane Protein 35, PMP35
Instance information
comment
2018 (1991) ,2018; see PEROXISOME ASSEMBLY FACTOR-1 1991-2017; PEROXISOMAL BIOGENESIS FACTOR 2 was indexed under MEMBRANE PROTEINS 1991-2017
identifier
D000074428