DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
Synonyms: EC 3.6.1.3, Proteins, MutS Homolog, MutS Homolog, Homolog, MutS, 0, MutS Homolog Protein, Protein, MutS Homolog, MutS Proteins, Homolog Protein, MutS, MutS Protein, Protein, MutS, Homolog Proteins, MutS, MutS Homolog Proteins, MutS Homologs
Instance information
2018
D000074080