A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.
Synonyms: CD50 Antigen, Antigen, CD50, 0, CD50 Antigens, Intercellular Adhesion Molecule 3, CDw50 Antigen, ICAM3, Antigen, CDw50, ICAM-3, Antigens, CD50, Intercellular Adhesion Molecule-3
Instance information
comment
2018
identifier
D000074001