A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of mostly mammals. Human betacoronaviruses include HUMAN ENTERIC CORONAVIRUS; HUMAN CORONAVIRUS OC43; MERS VIRUS; and SARS VIRUS. Members have either core transcription regulatory sequences of 5’-CUAAAC-3’ or 5’-CUAAAC-3’ and mostly have no ORF downstream to the N protein gene.

Synonyms: Pipistrellus bat coronavirus HKU5, Human coronavirus HKU1, txid694008, txid694007, txid694006, Rousettus bat coronavirus HKU9, HCoV-HKU1, txid694002, Betacoronavirus, Tylonycteris bat coronavirus HKU4, txid290028, Betacoronaviruses