A dioxygenase and alkylation repair homolog that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. It can also repair alkylated DNA containing 1-ethenoadenine in vitro. It has highest affinity for double-stranded DNA.

Synonyms: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase, DNA Oxidative Demethylase ALKBH2, AlkB Homolog 2, Alpha Ketoglutarate Dependent Dioxygenase, Oxy DC1 Protein, EC 1.14.11.33, Alpha ketoglutarate Dependent Dioxygenase AlkB Homolog 2, Alpha-ketoglutarate-Dependent Dioxygenase AlkB Homolog 2, Alkylated DNA Repair Protein AlkB Homolog 2