A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS.
Synonyms: DNA Oxidative Demethylase ALKBH1, ABH1, DNA Lyase, AlkB Homolog 1, Histone H2a Dioxygenase, EC 1.14.11.33, Alpha-Ketoglutarate-Dependent Dioxygenase ABH1, ALKBH Protein, ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase, DNA Lyase ABH1, Alkylated DNA Repair Protein AlkB Homolog 1, Alpha Ketoglutarate Dependent Dioxygenase ABH1
Instance information
comment
2017
identifier
D000071498