A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.
Synonyms: 0, OPC 14597, Abilify, 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone, Aripiprazol, OPC-14597, 82VFR53I78, Aripiprazole
Instance information
comment
2016; ARIPIPRAZOLE was indexed under QUINOLONES 1995-2015 and under PIPERAZINES 1995-2015 ,2016 (1995)
identifier
D000068180