The manipulation of STEM CELL culture conditions to induce cell differentiation into a particular cell type.

Procedures used for the induction of CELLULAR REPROGRAMMING to change the terminal phenotype of a cell, such as the generation of INDUCED PLURIPOTENT STEM CELLS from differentiated adult cells by the forced expression of specific genes.

The creation of a pluripotent stem cell or other cell type from an adult somatic cell by the forced expression of specific genes or other methods.

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