|
Paraproteinemia
|
HP_0031047 |
[An abnormal immunoglobulin or part of an Ig (light chain) in the circulation. Paraproteins are typically produced by a clonal population of B-cell derived plasma cells.] |
|
T-cell lymphoma/leukemia
|
HP_0005517 |
[A type of T-cell lymphoma in which cancerous T-cells may present in the blood (leukemia), lymph nodes (lymphoma), skin or in multiple areas.] |
|
obsolete Impaired neutrophil killing of staphylococci
|
HP_0005512 |
|
|
Increased megakaryocyte count
|
HP_0005513 |
[Increased megakaryocyte number, i.e., of platelet precursor cells, present in the bone marrow.] |
|
Transient erythroblastopenia
|
HP_0005510 |
[A transient reduction in the number of erythroblasts in the circulation.] |
|
Heinz body anemia
|
HP_0005511 |
[Anemia characterized by abnormal intracellular inclusions, composed of denatured hemoglobin, found on the membrane of red blood cells.] |
|
lamina of gray matter of spinal cord
|
UBERON_0016570 |
|
|
Increased mean corpuscular volume
|
HP_0005518 |
[Larger than normal size of erythrocytes.] |
|
Abnormal mean corpuscular volume
|
HP_0025065 |
[A deviation from normal of the mean corpuscular volume, or mean cell volume (MCV) of red blood cells, usually taken to be 80 to 100 femtoliters.] |
|
Reduced kininogen activity
|
HP_0005527 |
[Amount or activity of kininogen is below the lower limit of normal. Kininogen functions as a cofactor in the contact phase of the intrinsic blood coagulation cascade.] |
|
Bone marrow hypocellularity
|
HP_0005528 |
[A reduced number of hematopoietic cells present in the bone marrow relative to marrow fat.] |
|
Spontaneous hemolytic crises
|
HP_0005525 |
|
|
Lymphoid leukemia
|
HP_0005526 |
[A malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood. This category includes precursor or acute lymphoblastic leukemias and chronic leukemias.] |
|
proton-transporting two-sector ATPase complex
|
GO_0016469 |
[A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.] |
|
Macrocytic hemolytic disease
|
HP_0005524 |
|
|
Disseminated intravascular coagulation
|
HP_0005521 |
[Disseminated intravascular coagulation is characterized by the widespread activation of coagulation, which results in the intravascular formation of fibrin and ultimately thrombotic occlusion of small and midsize vessels.] |
|
Pyridoxine-responsive sideroblastic anemia
|
HP_0005522 |
[A type of sideroblastic anemia that is alleviated by pyridoxine (vitamin B-6) treatment.] |
|
Sideroblastic anemia
|
HP_0001924 |
[Sideroblastic anemia results from a defect in the incorporation of iron into the heme molecule. A sideroblast is an erythroblast that has stainable deposits of iron in cytoplasm (this can be demonstrated by Prussian blue staining).] |
|
Chronic disseminated intravascular coagulation
|
HP_0005520 |
[A chronic form of disseminated intravascular coagulation in which a persistent weak or intermittent activating stimulus is present and destruction and production of coagulation factors and platelets are balanced.] |
|
T cell chronic lymphocytic lymphoma/leukemia
|
HP_0005539 |
[A form of lymphoid leukemia or lymphoma in which too many T-cell lymphoblasts are found in the blood, bone marrow, and tissues. Leukemia or lymphoma classification depends on which feature is more prominent.] |