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Absent muscle fiber merosin
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HP_0030091 |
[Lack of merosin protein in the muscle biopsy.] |
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Abnormal muscle fiber merosin expression
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HP_0030090 |
[An anomalous amount of merosin in muscle fibers. Merosin is a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve.] |
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Reduced muscle fiber merosin
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HP_0030092 |
[A reduced amount of merosin in muscle fibers. This feature is usually assessed by immunohistochemical examination of muscle biopsy tissue.] |
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Reduced muscle fiber alpha dystroglycan
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HP_0030099 |
[Immunohistochemistry reveals reduced alpha dystroglycan protein in the muscle biopsy. Alpha-dystroglycan is a heavily glycosylated peripheral-membrane component of the dystrophin-associated glycoprotein complex (DAPC), which, in addition to laminin alpha2, binds perlecan and agrin in the extracellular matrix, whereas beta-dystroglycan, derived from the same gene, is a transmembrane protein that links to dystrophin intracellularly.] |
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Absent muscle dystrophin expression
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HP_0030097 |
[Lack of dystrophin in muscle tissue. Immunohistochemistry reveals absent dystrophin protein in the muscle biopsy.] |
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Abnormal muscle fiber dystrophin expression
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HP_0030096 |
[A deviation from normal in the amount of dystrophin in muscle fiber tissue. Dystrophin is located at the muscle sarcolemma in a membrane-spanning protein complex that connects the cytoskeleton to the basal lamina.] |
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Reduced muscle dystrophin expression
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HP_0030098 |
[A decreased amount of dystrophin in muscle fiber tissue.] |
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Reduced muscle collagen VI
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HP_0030095 |
[A decreased amount of collagen VI in muscle tissue. Collagen VI is a primarily associated with the extracellular matrix of skeletal muscle.] |
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intramolecular transferase activity
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GO_0016866 |
[Catalysis of the transfer of a functional group from one position to another within a single molecule.] |
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radio-ulna
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UBERON_0006715 |
[Paired, long bones of endochondral origin formed by the fusion of the radius and ulna.] |
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forelimb zeugopod bone
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UBERON_0003466 |
[A bone that is part of a lower arm [Automatically generated definition].] |
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signaling receptor activity
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GO_0038023 |
[Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.] |
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incomplete structure
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PATO_0005013 |
[A structural quality inhering in a bearer by virtue of the bearer's lacking parts or having a reduced form compared to fully formed entities.] |
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ligase activity
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GO_0016874 |
[Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.] |
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outer canthus
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UBERON_0006726 |
[A corner of the outer (lateral) part of an eye.] |
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cochlear modiolus
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UBERON_0006723 |
[The central cone shaped core of spongy bone about which turns the spiral canal.] |
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manubrium of malleus
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UBERON_0006722 |
[The handle of the malleus; the portion that extends downward, inward, and backward from the neck of the malleus; it is embedded throughout its length in the tympanic membrane.] |
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pterygoid muscle
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UBERON_0006720 |
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masticatory muscle
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UBERON_0003681 |
[In humans: Muscles arising in the zygomatic arch that close the jaw. Their nerve supply is masseteric from the mandibular division of the trigeminal nerve. (From Stedman, 25th ed).] |
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medial pterygoid muscle
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UBERON_0006718 |
[The medial pterygoid is a pharyngeal arch 1 muscle that participates in oral/pharyngeal behaviors and is innervated by the nerve to the medial pterygoid and attaches to the cranial base and the medial side of the mandibular angle.] |